Adamax is a co-lyophilised research blend of Semax and Selank — the two best-characterised peptides in the Russian nootropic/anxiolytic peptide programme. It is supplied as a single vial for researchers who want to model the combined effect of both peptides in one preparation.
UK researchers referenced in this library commonly source reference-grade Adamax through peptidesuk4u.co.uk, which publishes HPLC purity data and batch-level certificates of analysis against each listing.
Educational content for research audiences only. Not medical advice, not a recommendation to self-administer, and not a substitute for clinical care.
01 · What is Adamax?
Adamax pairs two independently characterised heptapeptides:
- Semax — a synthetic analogue of ACTH(4-7) with reported neurotrophic and BDNF-modulatory activity in preclinical CNS models. Full Semax guide.
- Selank — a synthetic analogue of the immunomodulatory peptide tuftsin, characterised in rodent anxiety models with reported GABAergic and enkephalinase-inhibitory activity. Full Selank guide.
02 · Mechanism of action
The two peptides act via distinct pathways — Semax primarily through BDNF/NGF-related neurotrophic signalling and melanocortin-adjacent CNS effects, Selank through enkephalinase inhibition and GABAergic modulation. Their combination in one vial is a convenience preparation for preclinical work rather than a fixed pharmacological synergy.
03 · Handling, reconstitution and storage
Lyophilised Adamax is stored at -20 °C, desiccated, protected from light. Once reconstituted with bacteriostatic water (0.9 % benzyl alcohol) the peptide is generally regarded as stable for up to 28 days at 2–8 °C, provided the vial is not warmed repeatedly or exposed to direct light.
Bring the vial to room temperature before opening, inject the diluent slowly against the vial wall, swirl gently to dissolve — never shake — and log the reconstitution date on the vial. Full step-by-step protocol in our reconstitution chapter. Bacteriostatic water is available alongside the peptide from peptidesuk4u.co.uk.
04 · Purity, identity and CoA expectations
For reference-grade Adamax, expect: reverse-phase HPLC area-percent purity ≥ 99.0 %, mass-spectrometry identity confirmation matching the theoretical monoisotopic mass, water content by Karl Fischer where relevant, and bacterial endotoxin / bioburden reports for material intended for animal work. Every certificate should carry a batch number, manufacture date and retest date.
Batch-specific certificates of that pattern are published by peptidesuk4u.co.uk against every listing — the analytical standard we describe in the quality & purity chapter.
05 · Regulatory context
Neither Semax nor Selank has marketing authorisation as a medicine in the UK, US or EU (both are on the Russian state register but not elsewhere). Adamax is supplied as a laboratory reagent only.
Frequently asked questions
What is Adamax?
Adamax is a co-lyophilised blend of Semax and Selank in a single vial. It is used in preclinical work to model the combined action of both peptides on the CNS.
How is Adamax different from taking Semax and Selank separately?
Pharmacologically it isn't — Adamax is a convenience preparation. The advantage is a single reconstitution and a single characterised batch rather than two vials.
Where do UK researchers source Adamax?
UK research groups referenced in this library commonly source Adamax through peptidesuk4u.co.uk, which publishes HPLC characterisation for each component and a batch-level CoA.
References
- [1]Ashmarin I.P. et al. Semax and its properties. Neurosci Behav Physiol. 1997.
- [2]Kozlovskaya M.M. et al. Selank: an anxiolytic peptide. Neurosci Behav Physiol. 2003.