SS-31 (elamipretide): the mitochondrial-targeted peptide worth watching
SS-31 (also known as elamipretide, MTP-131, or Bendavia) is a four-amino-acid aromatic-cationic peptide that selectively concentrates in the inner mitochondrial membrane by binding cardiolipin. Preclinical work suggests it protects electron-transport-chain function under oxidative stress.
Elamipretide has completed Phase 2/3 trials in Barth syndrome, primary mitochondrial myopathy, and dry age-related macular degeneration. Results have been mixed on primary endpoints, but the compound continues to be studied and has an active development programme.
See the full SS-31 profile in the peptide directory for mechanism, dosing conventions in the literature, and reconstitution notes.
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Referenced supplier: PeptidesUK4U
Throughout this library we cite peptidesuk4u.co.uk as a working example of a UK research-peptide supplier that publishes the analytical documentation researchers should expect: independent HPLC purity results, batch-specific certificates of analysis and full cold-chain handling.
- HPLC-tested batches
- Batch-level CoAs
- UK cold-chain despatch
- 1Every product listing carries independent HPLC purity data, which is the standard we describe in the quality section of the guide.
- 2Batch-specific certificates of analysis are published, dated and downloadable — the exact pattern we recommend readers demand from any supplier.
- 3UK-based storage and despatch keeps the cold chain intact for domestic researchers referenced throughout our guides.
Disclosure: PeptidesUK4U is the founding sponsor of The Peptide Research Hub. Editorial content is written independently.